Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp251 | Thyroid non cancer | ECE2018

Thyroid-specific mitochondrial dysfunction results in abnormal thyrotropin responses

Joung Kyong Hye , Lee Jung Uee , Kim Ji Min , Lee Sang-Hee , Kim Seong-Min , Kim Hyun Jin , Shong Minho

Background: Optimal production of cellular energy and metabolites in mitochondria is one of the most important factors in endocrine organs that accomplish the momentary adaptation to ligand stimulation, such as insulin secretion and aldosterone biosynthesis. Although it has been suggested that thyroid gland function is also largely dependent on mitochondrial function, functional behavior of thyroid gland on compromised mitochondrial function remained to be identified. In this ...